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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKR1B1Aldo_ket_red domain-containing protein. (313 aa)    
Predicted Functional Partners:
gclc
Glutamate-cysteine ligase, catalytic subunit.
   
 0.601
ENSAMXP00000029605
Uncharacterized protein.
   
 0.601
W5K9H7_ASTMX
Glyoxylate reductase/hydroxypyruvate reductase b; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.445
grhpr
Glyoxylate reductase/hydroxypyruvate reductase a; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.445
LOC103030986
Zgc:136493; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.445
taldo1
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 
 0.417
gss
Glutathione synthetase.
   
 0.415
glo1
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
  
 
 0.402
yipf6
Protein YIPF.
   
  
 0.401
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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