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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5KK43_ASTMXPeptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (411 aa)    
Predicted Functional Partners:
agt
Angiotensinogen; Belongs to the serpin family.
   
 0.729
ctsh
Cathepsin H; Belongs to the peptidase C1 family.
   
 0.581
LOC103042155
Cathepsin F; Belongs to the peptidase C1 family.
   
 0.534
gga1
Golgi-associated, gamma adaptin ear containing, ARF binding protein 1.
    
 0.533
ctsc
Cathepsin C; Belongs to the peptidase C1 family.
   
 0.528
Atp6ap2
ATPase H+ transporting accessory protein 2.
   
 0.525
ENSAMXP00000028791
ATPase H+ transporting accessory protein 2.
   
 0.525
ide
Insulin-degrading enzyme; Belongs to the peptidase M16 family.
     
 0.513
W5KWR5_ASTMX
Cathepsin Ba; Belongs to the peptidase C1 family.
   
 0.501
ENSAMXP00000037969
Cathepsin Bb; Belongs to the peptidase C1 family.
   
 0.501
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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