close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5KK75_ASTMXRho guanine nucleotide exchange factor (GEF) 11. (1384 aa)    
Predicted Functional Partners:
LOC103022306
Guanine nucleotide binding protein (G protein), alpha 13a.
    
 0.694
gna12
Guanine nucleotide binding protein (G protein) alpha 12a.
    
 0.694
GNA13
G protein subunit alpha 13.
    
 0.694
ENSAMXP00000042082
Guanine nucleotide binding protein (G protein), alpha 13b.
    
 0.694
LOC103031338
Ras homolog family member Cb.
   
 0.603
LOC103028705
Ras homolog gene family, member Aa.
   
 0.603
RHOB
Ras homolog family member B.
   
 0.603
LOC103029431
Uncharacterized protein.
   
 0.603
LOC103035456
Ras homolog family member Ca.
   
 0.603
LOC103027457
Ras homolog gene family, member Ab.
   
 0.603
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: low (32%) [HD]