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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dlgap5Discs, large (Drosophila) homolog-associated protein 5. (982 aa)    
Predicted Functional Partners:
kif11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.963
Aspm
ASH domain-containing protein.
   
  
 0.957
bub1
BUB1 mitotic checkpoint serine/threonine kinase.
   
  
 0.945
W5LBU2_ASTMX
Ttk protein kinase.
   
  
 0.932
melk
Non-specific serine/threonine protein kinase.
   
  
 0.932
nusap1
Nucleolar and spindle associated protein 1.
   
  
 0.931
pbk
PDZ binding kinase.
   
  
 0.931
LOC103041753
Si:dkeyp-115e12.6.
   
  
 0.930
cdc20
Cell division cycle 20 homolog.
   
  
 0.929
cdca8
Cell division cycle associated 8.
   
  
 0.925
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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