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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Nod1Nucleotide-binding oligomerization domain containing 1. (913 aa)    
Predicted Functional Partners:
RIPK2
Receptor interacting serine/threonine kinase 2.
   
 0.987
atg16l1
ATG16 autophagy related 16-like 1 (S. cerevisiae).
    
 0.942
sugt1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.
    
 0.937
Aamp
Angio-associated, migratory cell protein.
     
 0.651
rps27a
Ribosomal protein S27a.
    
  0.611
UBB
Ubiquitin B.
    
 0.595
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
  0.593
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.586
map3k7
Mitogen-activated protein kinase kinase kinase 7.
    
 0.549
Apaf1
Apoptotic peptidase activating factor 1.
    
 0.538
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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