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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
chrndCholinergic receptor, nicotinic, delta (muscle). (522 aa)    
Predicted Functional Partners:
LOC103042886
Cholinergic receptor, nicotinic, alpha 1 (muscle).
   
0.670
CHRNA1
Cholinergic receptor nicotinic alpha 1 subunit.
   
0.651
rapsn
Receptor-associated protein of the synapse, 43kD.
   
 
 0.587
W5JZQ7_ASTMX
Cholinergic receptor, nicotinic, alpha 2a (neuronal).
    
0.539
LOC103025036
Cholinergic receptor, nicotinic, alpha 4b.
    
0.539
LOC103031133
Cholinergic receptor, nicotinic, alpha 2b (neuronal).
    
0.539
W5LJM4_ASTMX
Cholinergic receptor, nicotinic, beta polypeptide 3a.
   
0.535
LOC103031723
Cholinergic receptor, nicotinic, beta 3b (neuronal).
   
0.535
ENSAMXP00000037126
Docking protein 7.
      
 0.518
MUSK
Muscle associated receptor tyrosine kinase.
    
 
 0.415
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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