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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
msh3DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1107 aa)    
Predicted Functional Partners:
msh2
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
0.999
ENSAMXP00000037285
MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).
 
 0.976
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.973
Pms1
PMS1 homolog 1, mismatch repair system component.
 
 0.964
W5KKB9_ASTMX
PMS1 homolog 2, mismatch repair system component.
 
 0.945
msh6
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
 
 
0.940
ENSAMXP00000043058
DNA_MISMATCH_REPAIR_2 domain-containing protein.
  
 
 
0.940
mlh3
MutL homolog 3 (E. coli).
  
 0.938
Snx8
Sorting nexin 8a.
   
   0.917
ENSAMXP00000047426
MutL_C domain-containing protein.
  
 0.913
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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