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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tbrg1Transforming growth factor beta regulator 1. (544 aa)    
Predicted Functional Partners:
ash2l
Ash2 like, histone lysine methyltransferase complex subunit.
    
 0.832
Rbbp5
Retinoblastoma binding protein 5.
    
 0.831
cenpn
Centromere protein N.
   
 0.707
ARHGEF17
Rho guanine nucleotide exchange factor (GEF) 17.
   
  
 0.695
hspa13
Heat shock protein 70 family, member 13.
    
 
 0.683
cops2
COP9 signalosome subunit 2.
   
  
 0.675
P2RY6
Pyrimidinergic receptor P2Y6.
      
 0.661
W5K4M9_ASTMX
Lysine (K)-specific demethylase 6A.
   
 0.639
W5L1S1_ASTMX
Lysine (K)-specific demethylase 6A, like.
   
 0.639
LOC103028490
Lysine (K)-specific demethylase 6B, b.
   
 0.639
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.