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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5KM20_ASTMXCollagen and calcium binding EGF domains 1. (381 aa)    
Predicted Functional Partners:
Vegfc
Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family.
    
 0.624
Adamts3
ADAM metallopeptidase with thrombospondin type 1 motif, 3.
      
 0.580
vegfd
Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family.
    
 0.569
W5K189_ASTMX
Fms-related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
      
 0.564
Sox18
SRY-box transcription factor 18.
      
 0.519
ENSAMXP00000034918
ADAM metallopeptidase with thrombospondin type 1 motif, 14.
      
 0.501
phf5a
PHD finger protein 5A.
      
 0.499
suclg2
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
      
 0.461
itga9
Integrin, alpha 9; Belongs to the integrin alpha chain family.
    
 0.428
PTPN14
Protein tyrosine phosphatase non-receptor type 14.
    
 0.413
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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