close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rhbdf1Rhomboid 5 homolog 1a (Drosophila). (747 aa)    
Predicted Functional Partners:
ENSAMXP00000040877
Uncharacterized protein.
 
      0.601
nprl3
NPR3-like, GATOR1 complex subunit.
      
 0.601
polr3k
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
      
 0.583
ddx47
DEAD (Asp-Glu-Ala-Asp) box polypeptide 47; Belongs to the DEAD box helicase family.
  
  
 0.541
UBE2O
Ubiquitin conjugating enzyme E2 O.
   
  
 0.538
LOC103041996
ADAM metallopeptidase domain 17b.
    
 0.525
W5LD95_ASTMX
ADAM metallopeptidase domain 17a.
    
 0.525
snrnp25
Small nuclear ribonucleoprotein 25.
      
 0.518
Mgrn1
Mahogunin, ring finger 1b.
      
 0.517
elavl3
ELAV-like protein; Belongs to the RRM elav family.
      
 0.501
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.