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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103026515Matrix metallopeptidase 20b (enamelysin). (492 aa)    
Predicted Functional Partners:
LOC103028836
TIMP metallopeptidase inhibitor 2b.
   
 0.630
LOC103024286
TIMP metallopeptidase inhibitor 2a.
   
 0.630
TIMP3
TIMP metallopeptidase inhibitor 3.
   
 0.598
W5LP43_ASTMX
Matrix metallopeptidase 14b (membrane-inserted).
  
0.560
dcn
Decorin; May affect the rate of fibrils formation.
   
 
 0.516
ENSAMXP00000032943
Matrix metallopeptidase 11b.
  
0.483
timp4
TIMP metallopeptidase inhibitor 4, tandem duplicate 3.
    
 0.480
scube1
Signal peptide, CUB domain, EGF-like 1.
   
 0.418
LOC103030172
Signal peptide, CUB domain, EGF-like 3.
   
 0.418
ENSAMXP00000054649
Signal peptide, CUB domain, EGF-like 2.
   
 0.418
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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