close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103024115Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. (556 aa)    
Predicted Functional Partners:
W5KXG7_ASTMX
Coiled-coil domain containing 47.
    
 
 0.865
LOC103042943
Nodal modulator.
    
 
 0.750
tmem147
Transmembrane protein 147.
    
 
 0.733
ENSAMXP00000032417
Uncharacterized protein.
    
 
 0.733
LOC103036990
SEC61 translocon alpha 1 subunit, like.
   
 
 0.709
LOC103023094
SEC61 translocon alpha 1 subunit.
   
 
 0.709
rpl4
Ribosomal protein L4.
    
   0.704
rpl11
Ribosomal protein L11; Belongs to the universal ribosomal protein uL5 family.
    
 
 0.665
Sec61b
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
    
   0.664
RPL27A
Ribosomal protein L27a; Belongs to the universal ribosomal protein uL15 family.
    
 
 0.657
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: low (26%) [HD]