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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ATAD3AATPase family AAA domain containing 3A. (600 aa)    
Predicted Functional Partners:
ecsit
ECSIT signalling integrator.
   
   0.862
ndufaf1
NADH:ubiquinone oxidoreductase complex assembly factor 1.
    
   0.822
phb
Prohibitin.
   
 
 0.645
atp6v1h
V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system.
   
  
 0.585
cdk5
Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.
   
  
 0.580
pgrmc1
Progesterone receptor membrane component 1; Belongs to the cytochrome b5 family.
      
 0.578
Tspo
Translocator protein.
      
 0.575
Star
Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.
      
 0.575
LOC103047478
Prohibitin.
   
 
 0.571
LOC103035142
Prohibitin.
   
 
 0.571
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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