Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
W5KN35_ASTMXCadherin, EGF LAG seven-pass G-type receptor 2; Belongs to the G-protein coupled receptor 2 family. (2674 aa)    
Predicted Functional Partners:
vangl2
Vang-like protein.
    
 0.683
ENSAMXP00000035360
Cadherin EGF LAG seven-pass G-type receptor 1a; Belongs to the G-protein coupled receptor 2 family.
      
 0.630
VANGL1
Vang-like protein.
    
 0.612
LOC103036576
Vang-like protein.
    
 0.612
LOC103047463
Prickle homolog 1a.
   
 0.605
LOC103021937
Prickle homolog 1b.
   
 0.589
Celsr3
Cadherin, EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family.
      
 0.583
LOC103040803
Cadherin EGF LAG seven-pass G-type receptor 1b; Belongs to the G-protein coupled receptor 2 family.
      
 0.537
prickle2
Prickle homolog 2b.
   
 0.519
fzd3
Frizzled class receptor 3b; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.491
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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