ireb2 protein (Astyanax mexicanus) - STRING interaction network

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ireb2

Iron-responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family. (971 aa)

Predicted Functional Partners:

ENSAMXP00000045461

0.987

cs

0.973

fbxl5

0.956

senp8

0.928

idh2

0.902

idh1

0.902

SUCLG1

0.880

skp1

0.847

sod2

0.817

sdhb

0.802

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000045461	SUCLG1	ENSAMXP00000045461	ENSAMXP00000005410	Malate synthase-like.	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	0.778
ENSAMXP00000045461	cs	ENSAMXP00000045461	ENSAMXP00000017056	Malate synthase-like.	Citrate synthase; Belongs to the citrate synthase family.	0.992
ENSAMXP00000045461	idh1	ENSAMXP00000045461	ENSAMXP00000015717	Malate synthase-like.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.896
ENSAMXP00000045461	idh2	ENSAMXP00000045461	ENSAMXP00000007638	Malate synthase-like.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.896
ENSAMXP00000045461	ireb2	ENSAMXP00000045461	ENSAMXP00000009000	Malate synthase-like.	Iron-responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family.	0.987
ENSAMXP00000045461	sdhb	ENSAMXP00000045461	ENSAMXP00000045772	Malate synthase-like.	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.983
ENSAMXP00000045461	senp8	ENSAMXP00000045461	ENSAMXP00000026468	Malate synthase-like.	SUMO peptidase family member, NEDD8 specific.	0.825
ENSAMXP00000045461	sod2	ENSAMXP00000045461	ENSAMXP00000028897	Malate synthase-like.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.733
SUCLG1	ENSAMXP00000045461	ENSAMXP00000005410	ENSAMXP00000045461	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	Malate synthase-like.	0.778
SUCLG1	cs	ENSAMXP00000005410	ENSAMXP00000017056	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	Citrate synthase; Belongs to the citrate synthase family.	0.944
SUCLG1	idh1	ENSAMXP00000005410	ENSAMXP00000015717	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.883
SUCLG1	idh2	ENSAMXP00000005410	ENSAMXP00000007638	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.883
SUCLG1	ireb2	ENSAMXP00000005410	ENSAMXP00000009000	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	Iron-responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family.	0.880
SUCLG1	sdhb	ENSAMXP00000005410	ENSAMXP00000045772	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.999
SUCLG1	sod2	ENSAMXP00000005410	ENSAMXP00000028897	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.	0.934
cs	ENSAMXP00000045461	ENSAMXP00000017056	ENSAMXP00000045461	Citrate synthase; Belongs to the citrate synthase family.	Malate synthase-like.	0.992
cs	SUCLG1	ENSAMXP00000017056	ENSAMXP00000005410	Citrate synthase; Belongs to the citrate synthase family.	Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.	0.944
cs	idh1	ENSAMXP00000017056	ENSAMXP00000015717	Citrate synthase; Belongs to the citrate synthase family.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.960
cs	idh2	ENSAMXP00000017056	ENSAMXP00000007638	Citrate synthase; Belongs to the citrate synthase family.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.960
cs	ireb2	ENSAMXP00000017056	ENSAMXP00000009000	Citrate synthase; Belongs to the citrate synthase family.	Iron-responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family.	0.973