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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Arrdc1Arrestin domain containing 1b. (447 aa)    
Predicted Functional Partners:
LOC103039731
Thioredoxin; Belongs to the thioredoxin family.
    
 0.672
LOC103040975
Thioredoxin; Belongs to the thioredoxin family.
    
 0.672
mrps18b
Mitochondrial ribosomal protein S18B.
      
 0.552
LOC103039823
NME/NM23 family member 8; Belongs to the NDK family.
    
 0.547
ENSAMXP00000031014
annotation not available
    
 0.522
W5K2F8_ASTMX
E3 ubiquitin-protein ligase.
    
 
 0.497
wwp1
E3 ubiquitin-protein ligase.
    
 
 0.497
xpo7
Exportin 7.
      
 0.493
W5KJZ4_ASTMX
Tumor susceptibility 101b.
    
 
 0.490
tsg101
Tumor susceptibility 101a.
    
 
 0.490
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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