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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5KNG6_ASTMXGuanylate cyclase. (1038 aa)    
Predicted Functional Partners:
LOC103036205
Ectonucleotide pyrophosphatase/phosphodiesterase 1.
     
 0.917
nudt2
Nudix (nucleoside diphosphate linked moiety X)-type motif 2.
     
 0.905
LOC103044212
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.901
itpa
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.
    
 0.901
mocs1
Molybdenum cofactor synthesis 1.
   
 
 0.839
LOC103032860
Uncharacterized protein.
    
 0.811
pde6c
Phosphodiesterase.
   
 0.792
pde6a
Phosphodiesterase.
   
 0.792
ENSAMXP00000031931
Phosphodiesterase.
     
 0.773
PDE1C
Phosphodiesterase.
     
 0.773
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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