close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103025255NADPH oxidase organizer 1a. (502 aa)    
Predicted Functional Partners:
LOC103041742
Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
    
 0.888
ENSAMXP00000049007
NADPH oxidase activator 1.
   
 0.877
ncf2
Neutrophil cytosolic factor 2.
   
 0.848
NOX4
NADPH oxidase 4.
   
 0.748
nox1
NADPH oxidase 1.
   
 0.743
W5LF28_ASTMX
NADPH oxidase, EF-hand calcium binding domain 5.
   
 0.732
duox1
Dual oxidase.
   
 0.698
ncf1
Neutrophil cytosolic factor 1.
      
0.692
LOC103031151
Cytochrome b-245, beta polypeptide (chronic granulomatous disease).
   
 0.683
xkrx
XK-related protein.
   
 0.674
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: low (28%) [HD]