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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103039881Chemokine (C-C motif) ligand 35, duplicate 2. (100 aa)    
Predicted Functional Partners:
LOC103044285
Chemokine (C-C motif) ligand 25b.
    
 0.577
ENSAMXP00000044719
SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family.
   
 0.573
cxcl12
Chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1); Belongs to the intercrine alpha (chemokine CxC) family.
   
 0.573
LOC103036716
C-X-C motif chemokine.
    
 0.559
LOC103027519
Atypical chemokine receptor 4a; Belongs to the G-protein coupled receptor 1 family.
  
 0.526
LOC107197015
Chemokine (C-C motif) ligand 25a.
    
 0.525
LOC103040606
Atypical chemokine receptor 4b; Belongs to the G-protein coupled receptor 1 family.
  
 0.505
LOC103034269
Uncharacterized protein.
   
  
 0.440
ENSAMXP00000028954
Chemokine (C-C motif) receptor 10; Belongs to the G-protein coupled receptor 1 family.
   
 0.440
LOC103027159
SCY domain-containing protein.
   
 0.432
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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