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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5KNU4_ASTMXSphingomyelin phosphodiesterase 3, neutral. (613 aa)    
Predicted Functional Partners:
smpd2
Sphingomyelin phosphodiesterase 2b, neutral membrane (neutral sphingomyelinase).
      
 0.692
smpd4
Sphingomyelin phosphodiesterase 4.
      
 0.673
LOC103029614
Receptor for activated C kinase 1.
    
 0.620
LOC103033914
WD_REPEATS_REGION domain-containing protein.
    
 0.620
wdr31
WD repeat domain 31.
    
 0.606
LOC103041009
Tumor necrosis factor b (TNF superfamily, member 2).
    
 0.536
W5LDA3_ASTMX
Neutral sphingomyelinase (N-SMase) activation associated factor.
     
 0.493
Lyst
Lysosomal trafficking regulator.
     
 0.460
W5KZH6_ASTMX
Uncharacterized protein.
     
 0.460
wdfy3
WD repeat and FYVE domain containing 3.
     
 0.460
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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