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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103025860Polycomb group ring finger 5a. (239 aa)    
Predicted Functional Partners:
rnf2
Ring finger protein 2.
    
 0.949
LOC103040710
Activator of transcription and developmental regulator AUTS2 b.
    
 0.907
RING1
Ring finger protein 1.
    
 0.895
W5KMY1_ASTMX
Fibrosin.
    
 0.818
csnk2b
Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.
    
 0.810
LOC103021606
YY1 associated factor 2.
    
 0.778
YAF2
YY1 associated factor 2.
    
 0.778
rybp
RING1 and YY1 binding protein b.
    
 0.776
LOC103038090
Chromobox homolog 6a.
    
 0.742
LOC103044980
Chromobox homolog 8b.
    
 0.732
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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