close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
traf2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (531 aa)    
Predicted Functional Partners:
Tradd
Tnfrsf1a-associated via death domain.
    
 0.995
tnfrsf1b
Tumor necrosis factor receptor superfamily, member 1B.
   
 0.980
fadd
Fas (tnfrsf6)-associated via death domain.
   
 0.977
map3k1
Mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase.
   
 0.970
LOC103047161
ADP-ribosylation factor 2b.
    
 0.970
map3k7
Mitogen-activated protein kinase kinase kinase 7.
   
 0.967
ripk1
Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.
   
 0.963
tab3
TGF-beta activated kinase 1 (MAP3K7) binding protein 3.
    
 0.963
LOC103031120
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
0.961
LOC111190374
Uncharacterized protein.
   
 0.961
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: medium (46%) [HD]