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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cfap221Si:ch73-222h13.1. (778 aa)    
Predicted Functional Partners:
lrguk
Leucine-rich repeats and guanylate kinase domain containing.
    
   0.806
cfap74
Calcium channel, voltage-dependent, L type, alpha 1D subunit, b.
   
 
 0.703
ENSAMXP00000046158
Si:dkey-208b23.5.
    
 
 0.692
dpy30
Dpy-30 histone methyltransferase complex regulatory subunit.
    
 
 0.606
polr3c
RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.599
CFAP69
Cilia and flagella associated protein 69.
    
   0.599
spag6
Sperm associated antigen 6.
    
 
 0.560
ENSAMXP00000030769
annotation not available
   
  
 0.553
ZNF830
Zinc finger protein 830.
      
 0.531
CALML6
Calmodulin like 6.
    
 
 0.517
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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