close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hoxc13Homeobox C13a. (306 aa)    
Predicted Functional Partners:
foxn1
Forkhead box N1.
   
 
 0.615
rnf41
Ring finger protein 41.
      
 0.608
rab27b
RAB27B, member RAS oncogene family.
   
  
 0.599
lef1
Lymphoid enhancer-binding factor 1.
    
 
 0.589
rab8a
RAB8A, member RAS oncogene family.
      
 0.584
six2
SIX homeobox 2a.
      
 0.556
LOC103040314
Muscle segment homeobox 2b.
   
  
0.535
LOC103025908
RAB9A, member RAS oncogene family.
      
 0.495
rab9a
RAB9A, member RAS oncogene family.
      
 0.495
W5KHG4_ASTMX
Forkhead box N4.
   
 
 0.484
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.