Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ccdc181Coiled-coil domain containing 181. (462 aa)    
Predicted Functional Partners:
mrpl30
Mitochondrial ribosomal protein L30.
      
 0.825
cfap100
Cilia and flagella associated protein 100.
      
 0.715
Ccdc9
Coiled-coil domain containing 9.
      
 0.713
ccdc113
Coiled-coil domain containing 113.
      
 0.712
Cfap58
Uncharacterized protein.
      
 0.710
W5KQ75_ASTMX
Coiled-coil domain containing 135.
      
 0.674
wdr78
WD repeat domain 78.
      
 0.640
W5LPP4_ASTMX
WD repeat-containing protein 35.
      
 0.637
Cenpv
Centromere protein V.
      
 0.630
sdhaf2
Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.
      
 0.597
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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