Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC103040137SET domain containing 1A, histone lysine methyltransferase. (2267 aa)    
Predicted Functional Partners:
Rbbp5
Retinoblastoma binding protein 5.
    
 0.968
wdr82
WD repeat domain 82.
   
 0.967
ash2l
Ash2 like, histone lysine methyltransferase complex subunit.
    
 0.967
Camkmt
Calmodulin-lysine N-methyltransferase.
     
 0.949
LOC103045901
CXXC finger protein 1b.
   
 0.931
LOC103028330
CXXC finger protein 1a.
   
 0.931
LOC103023146
WD_REPEATS_REGION domain-containing protein.
   
 0.910
wdr5
WD repeat domain 5.
   
 0.910
dpy30
Dpy-30 histone methyltransferase complex regulatory subunit.
    
 0.906
setd2
SET domain containing 2, histone lysine methyltransferase.
   
 0.897
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: low (38%) [HD]