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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103040137SET domain containing 1A, histone lysine methyltransferase. (2267 aa)    
Predicted Functional Partners:
Rbbp5
Retinoblastoma binding protein 5.
    
 0.950
ash2l
Ash2 like, histone lysine methyltransferase complex subunit.
    
 0.950
dpy30
Dpy-30 histone methyltransferase complex regulatory subunit.
    
 0.905
wdr82
WD repeat domain 82.
   
 0.897
LOC103045901
CXXC finger protein 1b.
   
 0.829
LOC103028330
CXXC finger protein 1a.
   
 0.829
LOC103023146
WD_REPEATS_REGION domain-containing protein.
   
 0.765
wdr5
WD repeat domain 5.
   
 0.765
UBB
Ubiquitin B.
   
 0.764
LOC103039404
WD repeat and SOCS box containing 2.
   
 0.751
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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