Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
agtAngiotensinogen; Belongs to the serpin family. (456 aa)    
Predicted Functional Partners:
ace
Angiotensin-converting enzyme.
    
 0.999
LOC103027843
Angiotensin II receptor, type 1b; Belongs to the G-protein coupled receptor 1 family.
    
 0.997
LOC103035052
Angiotensin II receptor, type 2; Belongs to the G-protein coupled receptor 1 family.
    
 0.997
LOC103027188
Angiotensin II receptor, type 1a; Belongs to the G-protein coupled receptor 1 family.
    
 0.995
AGTR2
Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family.
    
 0.995
ace2
Angiotensin-converting enzyme.
    
 0.984
Enpep
Aminopeptidase.
  
 0.984
Tmem27
Si:dkey-194e6.1.
    
 0.984
LOC103041285
Si:dkey-63b1.1; Belongs to the G-protein coupled receptor 1 family.
    
 0.970
LOC103041516
Bradykinin receptor B1; Belongs to the G-protein coupled receptor 1 family.
    
 0.966
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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