Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
trmt1ltRNA methyltransferase 1-like; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (697 aa)    
Predicted Functional Partners:
thumpd1
THUMP domain containing 1.
   
 
 0.813
eprs1
Glutamyl-prolyl-tRNA synthetase.
   
   0.804
nsun2
NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
   
 
 0.796
polr3f
DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
   
 
 0.792
swt1
SWT1 RNA endoribonuclease homolog.
   
  
 0.788
wdr74
WD repeat domain 74.
   
   0.787
dus2
Dihydrouridine synthase 2.
   
 
 0.784
ccdc90b
Coiled-coil domain containing 90B.
      
 0.770
tpk1
Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family.
      
 0.770
trub1
TruB pseudouridine (psi) synthase family member 1.
   
 
 0.751
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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