vps26a protein (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

vps26a

VPS26, retromer complex component A. (327 aa)

Predicted Functional Partners:

vps35

0.998

vps29

0.996

LOC103034698

0.965

vps26b

0.965

snx3

0.932

W5KII5_ASTMX

0.912

snx12

0.908

LOC103026625

0.897

snx27

0.897

Snx2

0.834

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103026625	LOC103034698	ENSAMXP00000010088	ENSAMXP00000003307	Sorting nexin 27a.	Vacuolar protein sorting 26 homolog B, like.	0.711
LOC103026625	Snx2	ENSAMXP00000010088	ENSAMXP00000013036	Sorting nexin 27a.	Sorting nexin 2.	0.425
LOC103026625	W5KII5_ASTMX	ENSAMXP00000010088	ENSAMXP00000007397	Sorting nexin 27a.	TBC1 domain family, member 5.	0.547
LOC103026625	snx12	ENSAMXP00000010088	ENSAMXP00000037546	Sorting nexin 27a.	Sorting nexin 12.	0.447
LOC103026625	snx3	ENSAMXP00000010088	ENSAMXP00000052805	Sorting nexin 27a.	Sorting nexin 3.	0.447
LOC103026625	vps26a	ENSAMXP00000010088	ENSAMXP00000009908	Sorting nexin 27a.	VPS26, retromer complex component A.	0.897
LOC103026625	vps26b	ENSAMXP00000010088	ENSAMXP00000047543	Sorting nexin 27a.	VPS26, retromer complex component B.	0.711
LOC103026625	vps29	ENSAMXP00000010088	ENSAMXP00000029237	Sorting nexin 27a.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.595
LOC103026625	vps35	ENSAMXP00000010088	ENSAMXP00000019093	Sorting nexin 27a.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.676
LOC103034698	LOC103026625	ENSAMXP00000003307	ENSAMXP00000010088	Vacuolar protein sorting 26 homolog B, like.	Sorting nexin 27a.	0.711
LOC103034698	Snx2	ENSAMXP00000003307	ENSAMXP00000013036	Vacuolar protein sorting 26 homolog B, like.	Sorting nexin 2.	0.722
LOC103034698	W5KII5_ASTMX	ENSAMXP00000003307	ENSAMXP00000007397	Vacuolar protein sorting 26 homolog B, like.	TBC1 domain family, member 5.	0.803
LOC103034698	snx12	ENSAMXP00000003307	ENSAMXP00000037546	Vacuolar protein sorting 26 homolog B, like.	Sorting nexin 12.	0.891
LOC103034698	snx27	ENSAMXP00000003307	ENSAMXP00000016931	Vacuolar protein sorting 26 homolog B, like.	Sorting nexin 27b.	0.711
LOC103034698	snx3	ENSAMXP00000003307	ENSAMXP00000052805	Vacuolar protein sorting 26 homolog B, like.	Sorting nexin 3.	0.891
LOC103034698	vps26a	ENSAMXP00000003307	ENSAMXP00000009908	Vacuolar protein sorting 26 homolog B, like.	VPS26, retromer complex component A.	0.965
LOC103034698	vps26b	ENSAMXP00000003307	ENSAMXP00000047543	Vacuolar protein sorting 26 homolog B, like.	VPS26, retromer complex component B.	0.900
LOC103034698	vps29	ENSAMXP00000003307	ENSAMXP00000029237	Vacuolar protein sorting 26 homolog B, like.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.973
LOC103034698	vps35	ENSAMXP00000003307	ENSAMXP00000019093	Vacuolar protein sorting 26 homolog B, like.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.983
Snx2	LOC103026625	ENSAMXP00000013036	ENSAMXP00000010088	Sorting nexin 2.	Sorting nexin 27a.	0.425