Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
W5KQQ4_ASTMXR-spondin 4. (276 aa)    
Predicted Functional Partners:
W5KF41_ASTMX
Leucine-rich repeat containing G protein-coupled receptor 4.
   
 0.995
znrf3
Zinc and ring finger 3.
    
 0.976
rnf43
RING-type domain-containing protein.
    
 0.968
LGR6
Leucine rich repeat containing G protein-coupled receptor 6.
    
 0.966
rspo1
R-spondin 1.
     
 0.923
Unc5a
Unc-5 netrin receptor A.
      
 0.915
rspo3
R-spondin 3.
     
 0.878
rspo2
R-spondin 2.
     
  0.868
LOC103032161
Si:dkey-7k24.5.
     
 0.777
Nkd2
NKD inhibitor of WNT signaling pathway 2a.
      
 0.665
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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