tmem208 protein (Astyanax mexicanus) - STRING interaction network

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[Homology]

Score

tmem208

Transmembrane protein 208. (171 aa)

Predicted Functional Partners:

atg9a

0.860

W5L1E4_ASTMX

0.860

xrcc3

0.671

get3

0.642

knl1

0.635

W5KMS1_ASTMX

0.635

Rad51c

0.635

get1

0.620

rad51

0.606

rad51d

0.606

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Rad51c	W5KMS1_ASTMX	ENSAMXP00000038451	ENSAMXP00000008883	RAD51 paralog C.	Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily.	0.664
Rad51c	rad51	ENSAMXP00000038451	ENSAMXP00000014064	RAD51 paralog C.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.986
Rad51c	rad51d	ENSAMXP00000038451	ENSAMXP00000050559	RAD51 paralog C.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents; Belongs to the RecA family. RAD51 subfamily.	0.968
Rad51c	tmem208	ENSAMXP00000038451	ENSAMXP00000009999	RAD51 paralog C.	Transmembrane protein 208.	0.635
Rad51c	xrcc3	ENSAMXP00000038451	ENSAMXP00000039378	RAD51 paralog C.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	0.998
W5KMS1_ASTMX	Rad51c	ENSAMXP00000008883	ENSAMXP00000038451	Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily.	RAD51 paralog C.	0.664
W5KMS1_ASTMX	rad51	ENSAMXP00000008883	ENSAMXP00000014064	Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.972
W5KMS1_ASTMX	rad51d	ENSAMXP00000008883	ENSAMXP00000050559	Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents; Belongs to the RecA family. RAD51 subfamily.	0.901
W5KMS1_ASTMX	tmem208	ENSAMXP00000008883	ENSAMXP00000009999	Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily.	Transmembrane protein 208.	0.635
W5KMS1_ASTMX	xrcc3	ENSAMXP00000008883	ENSAMXP00000039378	Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	0.974
W5L1E4_ASTMX	tmem208	ENSAMXP00000013656	ENSAMXP00000009999	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	Transmembrane protein 208.	0.860
atg9a	tmem208	ENSAMXP00000004935	ENSAMXP00000009999	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.	Transmembrane protein 208.	0.860
get1	get3	ENSAMXP00000053601	ENSAMXP00000000483	Guided entry of tail-anchored proteins factor 1.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.996
get1	tmem208	ENSAMXP00000053601	ENSAMXP00000009999	Guided entry of tail-anchored proteins factor 1.	Transmembrane protein 208.	0.620
get3	get1	ENSAMXP00000000483	ENSAMXP00000053601	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	Guided entry of tail-anchored proteins factor 1.	0.996
get3	tmem208	ENSAMXP00000000483	ENSAMXP00000009999	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	Transmembrane protein 208.	0.642
knl1	rad51	ENSAMXP00000000123	ENSAMXP00000014064	Kinetochore scaffold 1.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.922
knl1	rad51d	ENSAMXP00000000123	ENSAMXP00000050559	Kinetochore scaffold 1.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents; Belongs to the RecA family. RAD51 subfamily.	0.901
knl1	tmem208	ENSAMXP00000000123	ENSAMXP00000009999	Kinetochore scaffold 1.	Transmembrane protein 208.	0.635
knl1	xrcc3	ENSAMXP00000000123	ENSAMXP00000039378	Kinetochore scaffold 1.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	0.955