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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPN14Protein tyrosine phosphatase non-receptor type 14. (1229 aa)    
Predicted Functional Partners:
W5KB64_ASTMX
WW domain containing transcription regulator 1.
   
 
 0.695
W5L798_ASTMX
Yes-associated protein 1.
   
 
 0.695
klhl6
BTB domain-containing protein.
      
 0.692
angptl4
Angiopoietin-like 4.
    
 0.527
W5K834_ASTMX
Chloride channel, voltage-sensitive 5b; Belongs to the chloride channel (TC 2.A.49) family.
    
 
 0.502
LOC103036488
Chloride channel protein.
    
 
 0.502
LOC103025096
Chloride channel protein.
    
 
 0.502
wwc1
WW and C2 domain containing 1.
    
 
 0.502
clcn3
Chloride channel protein.
    
 
 0.502
ENSAMXP00000054698
WWC family member 3.
    
 
 0.502
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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