close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Nadsyn1NAD synthetase 1. (289 aa)    
Predicted Functional Partners:
nudt12
Nudix (nucleoside diphosphate linked moiety X)-type motif 12.
  
 
 0.981
Nmnat1
Nicotinamide-nucleotide adenylyltransferase.
  
 
 0.976
nmnat3
Nicotinamide-nucleotide adenylyltransferase.
  
 
 0.976
nmnat2
Nicotinamide nucleotide adenylyltransferase 2.
  
 
 0.975
Sirt1
Deacetylase sirtuin-type domain-containing protein.
    
 0.947
LOC103032176
NAD kinase b.
    
 0.945
nadk
NAD kinase a.
    
 0.945
nadk2
NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor.
     
 0.939
sirt7
Sirtuin 7.
    
 0.936
sirt3
NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.
    
 0.936
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.