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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
card11Caspase recruitment domain family, member 11. (1126 aa)    
Predicted Functional Partners:
Bcl10
BCL10 immune signaling adaptor.
    
 0.975
malt1
MALT paracaspase 1.
    
 0.886
W5LC84_ASTMX
MALT paracaspase 3.
    
 0.886
LOC103040508
MALT paracaspase 2.
    
 0.886
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.841
map3k7
Mitogen-activated protein kinase kinase kinase 7.
   
 0.820
W5L0T6_ASTMX
Inhibitor of nuclear factor kappa B kinase subunit beta.
   
 0.812
W5K3S5_ASTMX
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
   
 0.790
ENSAMXP00000032772
Phorbol-ester/DAG-type domain-containing protein.
   
 0.790
LOC103036366
Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
   
 0.790
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.