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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5KRJ8_ASTMXRho guanine nucleotide exchange factor (GEF) 28a. (1701 aa)    
Predicted Functional Partners:
LOC103028705
Ras homolog gene family, member Aa.
   
 0.618
LOC103031338
Ras homolog family member Cb.
   
 0.608
RHOB
Ras homolog family member B.
   
 0.608
LOC103029431
Uncharacterized protein.
   
 0.608
LOC103035456
Ras homolog family member Ca.
   
 0.608
LOC103027457
Ras homolog gene family, member Ab.
   
 0.608
Cgn
Si:dkey-238m4.3.
     
 0.518
LOC103027302
Rho family GTPase 1a.
   
 0.518
LOC103021440
Rho family GTPase 3.
   
 0.512
rnd1
Rho family GTPase 1b.
   
 0.512
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.