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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5KS08_ASTMXAryl hydrocarbon receptor nuclear translocator-like 1b. (605 aa)    
Predicted Functional Partners:
W5KHP9_ASTMX
Neuronal PAS domain protein 2.
   
0.842
LOC103025395
Clock circadian regulator b.
   
0.842
Clock
Clock circadian regulator a.
   
0.826
npas4
Neuronal PAS domain protein 4a.
    
0.776
W5KF77_ASTMX
Uncharacterized protein.
    
0.763
LOC103039499
Uncharacterized protein.
    
0.763
ENSAMXP00000027502
Cryptochrome circadian regulator 4.
   
 0.749
per3
Period circadian clock 3.
    
0.687
LOC103033595
Period circadian clock 1b.
    
0.687
LOC103027542
Period circadian clock 1a.
    
0.686
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.