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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103036066Uncharacterized protein; Belongs to the peptidase C14A family. (305 aa)    
Predicted Functional Partners:
Apaf1
Apoptotic peptidase activating factor 1.
    
 0.798
cenpn
Centromere protein N.
   
 0.774
cenpi
Centromere protein I.
   
 0.744
cenpm
Proliferation associated nuclear element.
   
 0.718
cenpq
Uncharacterized protein.
   
 0.712
LOC103029186
Centromere protein O.
   
 0.697
ENSAMXP00000045807
CENP-T_C domain-containing protein.
   
 0.693
cenpk
Centromere protein K.
   
 0.692
ENSAMXP00000029920
Centromere protein H.
   
 0.688
ENSAMXP00000031533
Uncharacterized protein.
   
 0.677
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.