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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5KSM1_ASTMXATPase family AAA domain containing 5a. (1807 aa)    
Predicted Functional Partners:
rfc3
Replication factor C (activator 1) 3.
   
 0.981
Rfc4
Replication factor C (activator 1) 4.
   
 0.976
rfc5
Replication factor C (activator 1) 5.
   
 0.975
Rfc2
Replication factor C (activator 1) 2.
   
 0.972
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.967
ENSAMXP00000041115
WD repeat and HMG-box DNA binding protein 1.
   
 
 0.908
wrn
WRN RecQ like helicase.
   
 0.905
exo1
Exonuclease 1.
   
 0.905
fancm
Uncharacterized protein.
   
 0.902
rad17
RAD17 checkpoint clamp loader component.
   
 0.897
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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