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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
W5KSP2_ASTMXPotassium voltage-gated channel, subfamily H (eag-related), member 2a. (1115 aa)    
Predicted Functional Partners:
kcnq1
Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family.
     
 0.887
LOC103032692
Potassium voltage-gated channel, Shal-related subfamily, member 3; Belongs to the potassium channel family.
    
 0.720
W5KJY4_ASTMX
Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
    
 0.652
LOC103027221
Potassium channel, subfamily K, member 5b; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
    
 
 0.622
KCNE2
Potassium voltage-gated channel subfamily E regulatory subunit 2.
    
 0.591
W5KV56_ASTMX
Ryanodine receptor 2b (cardiac).
      
 0.573
gins3
GINS complex subunit 3.
      
 0.573
Smg8
SMG8 nonsense mediated mRNA decay factor.
      
 0.524
scn3b
Sodium channel, voltage-gated, type III, beta.
   
  
 0.501
LOC103030516
Potassium inwardly-rectifying channel, subfamily J, member 2b.
      
 0.500
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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