W5KSQ3_ASTMX protein (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

W5KSQ3_ASTMX

L3MBTL histone methyl-lysine binding protein 3. (490 aa)

Predicted Functional Partners:

rnf2

0.616

RING1

0.616

Tp53

0.573

LOC103037427

0.573

eed

0.551

ENSAMXP00000048969

0.503

Mphosph8

0.503

rybp

0.492

LOC103044866

0.492

LOC103021606

0.492

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAMXP00000048969	LOC103021606	ENSAMXP00000048969	ENSAMXP00000041651	ANK_REP_REGION domain-containing protein.	YY1 associated factor 2.	0.515
ENSAMXP00000048969	LOC103044866	ENSAMXP00000048969	ENSAMXP00000035979	ANK_REP_REGION domain-containing protein.	RING1 and YY1 binding protein a.	0.515
ENSAMXP00000048969	Mphosph8	ENSAMXP00000048969	ENSAMXP00000054532	ANK_REP_REGION domain-containing protein.	Chromo domain-containing protein.	0.545
ENSAMXP00000048969	RING1	ENSAMXP00000048969	ENSAMXP00000046288	ANK_REP_REGION domain-containing protein.	Ring finger protein 1.	0.715
ENSAMXP00000048969	W5KSQ3_ASTMX	ENSAMXP00000048969	ENSAMXP00000010615	ANK_REP_REGION domain-containing protein.	L3MBTL histone methyl-lysine binding protein 3.	0.503
ENSAMXP00000048969	rnf2	ENSAMXP00000048969	ENSAMXP00000005730	ANK_REP_REGION domain-containing protein.	Ring finger protein 2.	0.715
ENSAMXP00000048969	rybp	ENSAMXP00000048969	ENSAMXP00000028552	ANK_REP_REGION domain-containing protein.	RING1 and YY1 binding protein b.	0.515
LOC103021606	ENSAMXP00000048969	ENSAMXP00000041651	ENSAMXP00000048969	YY1 associated factor 2.	ANK_REP_REGION domain-containing protein.	0.515
LOC103021606	Mphosph8	ENSAMXP00000041651	ENSAMXP00000054532	YY1 associated factor 2.	Chromo domain-containing protein.	0.508
LOC103021606	RING1	ENSAMXP00000041651	ENSAMXP00000046288	YY1 associated factor 2.	Ring finger protein 1.	0.953
LOC103021606	W5KSQ3_ASTMX	ENSAMXP00000041651	ENSAMXP00000010615	YY1 associated factor 2.	L3MBTL histone methyl-lysine binding protein 3.	0.492
LOC103021606	rnf2	ENSAMXP00000041651	ENSAMXP00000005730	YY1 associated factor 2.	Ring finger protein 2.	0.897
LOC103037427	Tp53	ENSAMXP00000035025	ENSAMXP00000021366	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.904
LOC103037427	W5KSQ3_ASTMX	ENSAMXP00000035025	ENSAMXP00000010615	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	L3MBTL histone methyl-lysine binding protein 3.	0.573
LOC103044866	ENSAMXP00000048969	ENSAMXP00000035979	ENSAMXP00000048969	RING1 and YY1 binding protein a.	ANK_REP_REGION domain-containing protein.	0.515
LOC103044866	Mphosph8	ENSAMXP00000035979	ENSAMXP00000054532	RING1 and YY1 binding protein a.	Chromo domain-containing protein.	0.508
LOC103044866	RING1	ENSAMXP00000035979	ENSAMXP00000046288	RING1 and YY1 binding protein a.	Ring finger protein 1.	0.839
LOC103044866	W5KSQ3_ASTMX	ENSAMXP00000035979	ENSAMXP00000010615	RING1 and YY1 binding protein a.	L3MBTL histone methyl-lysine binding protein 3.	0.492
LOC103044866	rnf2	ENSAMXP00000035979	ENSAMXP00000005730	RING1 and YY1 binding protein a.	Ring finger protein 2.	0.839
Mphosph8	ENSAMXP00000048969	ENSAMXP00000054532	ENSAMXP00000048969	Chromo domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.545