LOC103023715 protein (Astyanax mexicanus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LOC103023715

Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family. (862 aa)

Predicted Functional Partners:

nrp1

0.903

Plxna4

0.690

W5K3K3_ASTMX

0.646

mst1r

0.646

W5LTS7_ASTMX

0.646

W5K1E9_ASTMX

0.645

cdk5

0.602

LOC103026658

0.579

plxna1

0.579

W5LE75_ASTMX

0.579

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103023715	LOC103026658	ENSAMXP00000010642	ENSAMXP00000004250	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family.	Plexin A1a.	0.579
LOC103023715	Plxna4	ENSAMXP00000010642	ENSAMXP00000038994	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family.	Plexin A4.	0.690
LOC103023715	W5K1E9_ASTMX	ENSAMXP00000010642	ENSAMXP00000001409	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family.	Plexin A2.	0.645
LOC103023715	W5K3K3_ASTMX	ENSAMXP00000010642	ENSAMXP00000002164	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family.	MET proto-oncogene, receptor tyrosine kinase.	0.646
LOC103023715	W5LE75_ASTMX	ENSAMXP00000010642	ENSAMXP00000018137	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family.	Plexin A3.	0.579
LOC103023715	W5LTS7_ASTMX	ENSAMXP00000010642	ENSAMXP00000026541	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family.	Macrophage stimulating 1 receptor a.	0.646
LOC103023715	cdk5	ENSAMXP00000010642	ENSAMXP00000013636	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family.	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	0.602
LOC103023715	mst1r	ENSAMXP00000010642	ENSAMXP00000007316	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family.	Macrophage stimulating 1 receptor b.	0.646
LOC103023715	nrp1	ENSAMXP00000010642	ENSAMXP00000030823	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family.	Neuropilin; Belongs to the neuropilin family.	0.903
LOC103023715	plxna1	ENSAMXP00000010642	ENSAMXP00000016691	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family.	Sema domain-containing protein.	0.579
LOC103026658	LOC103023715	ENSAMXP00000004250	ENSAMXP00000010642	Plexin A1a.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family.	0.579
LOC103026658	W5K3K3_ASTMX	ENSAMXP00000004250	ENSAMXP00000002164	Plexin A1a.	MET proto-oncogene, receptor tyrosine kinase.	0.425
LOC103026658	W5LTS7_ASTMX	ENSAMXP00000004250	ENSAMXP00000026541	Plexin A1a.	Macrophage stimulating 1 receptor a.	0.425
LOC103026658	cdk5	ENSAMXP00000004250	ENSAMXP00000013636	Plexin A1a.	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	0.464
LOC103026658	mst1r	ENSAMXP00000004250	ENSAMXP00000007316	Plexin A1a.	Macrophage stimulating 1 receptor b.	0.425
LOC103026658	nrp1	ENSAMXP00000004250	ENSAMXP00000030823	Plexin A1a.	Neuropilin; Belongs to the neuropilin family.	0.682
Plxna4	LOC103023715	ENSAMXP00000038994	ENSAMXP00000010642	Plexin A4.	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa; Belongs to the semaphorin family.	0.690
Plxna4	W5K3K3_ASTMX	ENSAMXP00000038994	ENSAMXP00000002164	Plexin A4.	MET proto-oncogene, receptor tyrosine kinase.	0.425
Plxna4	W5LTS7_ASTMX	ENSAMXP00000038994	ENSAMXP00000026541	Plexin A4.	Macrophage stimulating 1 receptor a.	0.425
Plxna4	cdk5	ENSAMXP00000038994	ENSAMXP00000013636	Plexin A4.	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily.	0.464