close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5KSU1_ASTMXSi:ch211-137a8.2. (620 aa)    
Predicted Functional Partners:
W5KNM3_ASTMX
SUN domain-containing protein.
    
 0.782
ENSAMXP00000029807
SUN domain-containing protein.
    
 0.782
ENSAMXP00000050923
Si:dkey-92f12.2.
    
 0.702
eny2
Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...]
    
 0.494
Trrap
Transformation/transcription domain-associated protein; Belongs to the PI3/PI4-kinase family.
    
 0.488
tada3
Transcriptional adaptor 3 (NGG1 homolog, yeast)-like.
    
 0.459
supt3h
SPT3 homolog, SAGA and STAGA complex component.
    
 0.446
W5KJM9_ASTMX
Uncharacterized protein.
    
 0.438
ENSAMXP00000031362
Uncharacterized protein.
    
 0.438
ENSAMXP00000037400
Uncharacterized protein.
    
 0.438
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: low (32%) [HD]