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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103043061Si:ch211-137a8.4. (617 aa)    
Predicted Functional Partners:
fancm
Uncharacterized protein.
    
 0.595
pold2
Polymerase (DNA directed), delta 2, regulatory subunit.
    
 0.543
ENSAMXP00000046361
Zinc finger protein 865.
  
  0.539
mus81
MUS81 structure-specific endonuclease subunit.
    
 0.519
pold1
DNA polymerase.
   
 0.518
LOC103023235
Survival of motor neuron 1, telomeric.
    
 0.515
W5L9M7_ASTMX
Si:dkeyp-69b9.6.
  
  0.495
ENSAMXP00000034669
Cerebellin 11.
  
 
  0.486
W5KLC2_ASTMX
Uncharacterized protein.
  
     0.470
snrpd2
Small nuclear ribonucleoprotein Sm D2.
    
 0.465
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.