Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tmem69Transmembrane protein 69. (250 aa)    
Predicted Functional Partners:
gpbp1l1
GC-rich promoter binding protein 1-like 1.
      
 0.887
txndc12
Thioredoxin domain containing 12 (endoplasmic reticulum).
      
 0.754
metap1
Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
   
  
 0.728
W5LRD2_ASTMX
Importin 9.
      
 0.653
Mast2
Microtubule associated serine/threonine kinase 2.
      
 0.643
ccdc137
Coiled-coil domain containing 137.
      
 0.607
spice1
Spindle and centriole associated protein 1.
      
 0.602
ankrd10
Ankyrin repeat domain 10a.
      
 0.517
dleu7
Si:ch73-160h15.3.
      
 0.514
gosr1
Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.
      
 0.496
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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