Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EPB41L2Erythrocyte membrane protein band 4.1 like 2. (355 aa)    
Predicted Functional Partners:
ENSAMXP00000041886
Uncharacterized protein.
 
      0.867
W5L1R1_ASTMX
Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.
   
 0.643
Cask
Calcium/calmodulin-dependent serine protein kinase a; Belongs to the MAGUK family.
   
 0.643
Mpp1
Membrane protein, palmitoylated 1; Belongs to the MAGUK family.
   
 0.544
sptan1
Spectrin alpha, non-erythrocytic 1.
   
 0.500
eif3a
Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
    
   0.492
W5L5A6_ASTMX
Polymerase (RNA) III (DNA directed) polypeptide G.
      
 0.475
PTPN20
Protein tyrosine phosphatase non-receptor type 20.
 
      0.461
mpp6
Membrane protein, palmitoylated 6a (MAGUK p55 subfamily member 6); Belongs to the MAGUK family.
    
 0.457
LOC107196972
Membrane protein, palmitoylated 2a (MAGUK p55 subfamily member 2); Belongs to the MAGUK family.
    
 0.457
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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