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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5KT92_ASTMXUncharacterized protein. (287 aa)    
Predicted Functional Partners:
ENSAMXP00000033034
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 0.582
zfand4
Zinc finger, AN1-type domain 4.
    
 0.507
dph3
Diphthamide biosynthesis 3.
    
 
 0.451
LOC103021796
Uncharacterized protein.
    
 0.425
LOC103027984
RAB guanine nucleotide exchange factor (GEF) 1, like.
    
 0.425
rabgef1
RAB guanine nucleotide exchange factor (GEF) 1.
    
 0.425
rnf8
E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]
   
  0.421
nek7
NIMA-related kinase 7; Belongs to the protein kinase superfamily.
    
 0.409
W5LKL9_ASTMX
NIMA-related kinase 6; Belongs to the protein kinase superfamily.
    
 0.409
Adgrb3
Adhesion G protein-coupled receptor B3; Belongs to the G-protein coupled receptor 2 family.
    
 0.400
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.