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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lats1Large tumor suppressor kinase 1. (1109 aa)    
Predicted Functional Partners:
LOC103036920
MOB kinase activator 1Ba.
   
 0.951
sav1
Salvador family WW domain containing protein 1.
    
 0.949
W5KB64_ASTMX
WW domain containing transcription regulator 1.
    
 0.947
W5L798_ASTMX
Yes-associated protein 1.
    
 0.946
LOC103031464
MOB kinase activator 1A.
    
 0.936
LOC103043555
MOB kinase activator 1Bb.
    
 0.929
STK4
Serine/threonine kinase 4.
    
0.882
stk3
Serine/threonine kinase 3 (STE20 homolog, yeast).
    
0.882
ENSAMXP00000052482
Si:dkey-266m15.5.
    
 0.878
LOC103036249
Angiomotin.
    
 0.795
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.