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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pde6aPhosphodiesterase. (863 aa)    
Predicted Functional Partners:
pde6g
Phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog b.
   
 0.986
LOC103037569
Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1.
   
 0.984
gnb1
Guanine nucleotide binding protein (G protein), beta polypeptide 1a.
     
 0.954
LOC103026630
Phosphodiesterase 6H, cGMP-specific, cone, gamma, paralog a.
   
 
 0.944
LOC103023645
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
 
 0.934
LOC103023031
Guanine nucleotide binding protein (G protein), beta polypeptide 1b.
     
 0.928
LOC103038783
Guanylate cyclase.
   
 0.896
LOC103022544
Uncharacterized protein.
   
 0.803
W5KNG6_ASTMX
Guanylate cyclase.
   
 0.792
gucy2c
Guanylate cyclase.
   
 0.792
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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