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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103043694Uncharacterized protein. (465 aa)    
Predicted Functional Partners:
LOC111194997
Interleukin-1.
   
 0.994
ENSAMXP00000046425
Interleukin-1.
   
 0.994
W5KW72_ASTMX
Uncharacterized protein.
   
 
0.955
LOC103041009
Tumor necrosis factor b (TNF superfamily, member 2).
      
 0.533
ENSAMXP00000048561
Protein phosphatase 1, regulatory subunit 13Ba.
   
  
 0.524
irak1bp1
Interleukin-1 receptor-associated kinase 1 binding protein 1.
      
 0.521
LOC103046085
Coagulation factor VII, like.
    
 0.499
LOC103046381
Coagulation factor VII.
    
 0.499
il10
Interleukin 10.
   
 
 0.494
socs1
Suppressor of cytokine signaling 1a.
    
 
 0.458
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.