dicer1 protein (Astyanax mexicanus) - STRING interaction network

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Score

dicer1

Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily. (1870 aa)

Predicted Functional Partners:

tarbp2

0.975

prkra

0.975

dgcr8

0.962

stau2

0.935

W5LBU5_ASTMX

0.935

ago2

0.899

mrps9

0.881

Mrps6

0.861

W5K3J1_ASTMX

0.859

W5K4D5_ASTMX

0.859

Your Current Organism:

Astyanax mexicanus

NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Mrps6	dicer1	ENSAMXP00000026990	ENSAMXP00000011018	Mitochondrial ribosomal protein S6.	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.	0.861
Mrps6	mrps9	ENSAMXP00000026990	ENSAMXP00000009900	Mitochondrial ribosomal protein S6.	Mitochondrial ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.999
W5K3J1_ASTMX	W5LBU5_ASTMX	ENSAMXP00000002152	ENSAMXP00000017307	Argonaute RISC component 1; Belongs to the argonaute family.	Staufen double-stranded RNA binding protein 1.	0.637
W5K3J1_ASTMX	dicer1	ENSAMXP00000002152	ENSAMXP00000011018	Argonaute RISC component 1; Belongs to the argonaute family.	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.	0.859
W5K3J1_ASTMX	prkra	ENSAMXP00000002152	ENSAMXP00000036403	Argonaute RISC component 1; Belongs to the argonaute family.	Protein kinase, interferon-inducible double stranded RNA dependent activator.	0.759
W5K3J1_ASTMX	stau2	ENSAMXP00000002152	ENSAMXP00000000463	Argonaute RISC component 1; Belongs to the argonaute family.	Staufen double-stranded RNA binding protein 2.	0.637
W5K3J1_ASTMX	tarbp2	ENSAMXP00000002152	ENSAMXP00000017163	Argonaute RISC component 1; Belongs to the argonaute family.	RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...]	0.759
W5K4D5_ASTMX	W5LBU5_ASTMX	ENSAMXP00000002446	ENSAMXP00000017307	Argonaute RISC catalytic component 3a; Belongs to the argonaute family.	Staufen double-stranded RNA binding protein 1.	0.637
W5K4D5_ASTMX	dicer1	ENSAMXP00000002446	ENSAMXP00000011018	Argonaute RISC catalytic component 3a; Belongs to the argonaute family.	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.	0.859
W5K4D5_ASTMX	prkra	ENSAMXP00000002446	ENSAMXP00000036403	Argonaute RISC catalytic component 3a; Belongs to the argonaute family.	Protein kinase, interferon-inducible double stranded RNA dependent activator.	0.759
W5K4D5_ASTMX	stau2	ENSAMXP00000002446	ENSAMXP00000000463	Argonaute RISC catalytic component 3a; Belongs to the argonaute family.	Staufen double-stranded RNA binding protein 2.	0.637
W5K4D5_ASTMX	tarbp2	ENSAMXP00000002446	ENSAMXP00000017163	Argonaute RISC catalytic component 3a; Belongs to the argonaute family.	RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...]	0.759
W5LBU5_ASTMX	W5K3J1_ASTMX	ENSAMXP00000017307	ENSAMXP00000002152	Staufen double-stranded RNA binding protein 1.	Argonaute RISC component 1; Belongs to the argonaute family.	0.637
W5LBU5_ASTMX	W5K4D5_ASTMX	ENSAMXP00000017307	ENSAMXP00000002446	Staufen double-stranded RNA binding protein 1.	Argonaute RISC catalytic component 3a; Belongs to the argonaute family.	0.637
W5LBU5_ASTMX	ago2	ENSAMXP00000017307	ENSAMXP00000054811	Staufen double-stranded RNA binding protein 1.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.637
W5LBU5_ASTMX	dicer1	ENSAMXP00000017307	ENSAMXP00000011018	Staufen double-stranded RNA binding protein 1.	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.	0.935
ago2	W5LBU5_ASTMX	ENSAMXP00000054811	ENSAMXP00000017307	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Staufen double-stranded RNA binding protein 1.	0.637
ago2	dgcr8	ENSAMXP00000054811	ENSAMXP00000017946	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	DGCR8 microprocessor complex subunit.	0.695
ago2	dicer1	ENSAMXP00000054811	ENSAMXP00000011018	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.	0.899
ago2	prkra	ENSAMXP00000054811	ENSAMXP00000036403	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Protein kinase, interferon-inducible double stranded RNA dependent activator.	0.759